Slate's Political Gabfest | Every Friday. Editor of Slate Magazine David Plotz, with Emily Bazelon and John Dickerson. The number one podcast on US politics.
In Our Times | From BBC Radio 4. Every Thursday morning Melvyn Bragg interviews three guests about anything from Edward Munch to Quantum Gravity. Undisputed master of the History of Ideas, only occasionally challenged by Entitled Opinions.
This Week in Google | Wednesdays. Great show. TWiT-founder Leo Laporte discuss the current state of cloud computing Gina Trippani, Jeff Jarvis and a guest. The Gillmor Gang covers the same beat with a different tone, less polished, tends to dig deeper, not always to great effect. This Week In Tech, the 2-hr flagship show of the TWiT network, available Monday mornings, is sometimes good but often has too much of the everything's-a-joke TWiT humour.
Friday Night Comedy | BBC Radio 4 pokes fun at the news every Friday evening. The excellent News Quiz alternates with the less funny Now Show every couple of months (we're currently in a News Quiz phase).
Global News | Also from the BBC. Updated twice daily except weekends, including at 2-3 in the morning, which means that the truly podcast-addicted can always start the day here. Somewhat obsessed with interviewing random people about whatever plight they're in.
The Economist | More current affairs. The 'All Audio' edition updates sporadically throughout the week whereas the 'Editor's Highlights' is a one hour block of readings from the latest issue of the magazine released every Friday.
Triangulation | Near-weekly one hour show with Leo Laporte and Tom Merrit. Great stuff if the guest is good and fortunately they manage some seriously good guests, including Steve Martin, Kevin Kelly, Ray Kurzweil, Jeri Ellsworth, the list goes on, check the archive.
Start the Week with Andrew Marr | Monday morning. Hit-and-miss, too much artistic sentiment but occasionally very good (Monday morning, you take what you can get). Nearly got bumped off the list by Great Lives, also from the BBC.
FourCast | Futurism from the TWiT network, updated once or twice a month. Only just started listening to this. A bit too light-hearted for my taste but with Changesurfer Radio seemingly out of the loop a futurist has to get his fix somewhere. Futures in Biotech, also from the TWiT network, works too.